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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CAMKK1 All Species: 24.85
Human Site: S443 Identified Species: 54.67
UniProt: Q8N5S9 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8N5S9 NP_115670.1 505 55735 S443 N S V R L I P S W T T V I L V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001091843 505 55717 S443 N S V R L I P S W T T V I L V
Dog Lupus familis XP_868554 482 53098 H423 P L P S E E E H C S V V E V T
Cat Felis silvestris
Mouse Mus musculus Q8VBY2 505 55819 S443 N S V R L I P S W T T V I L V
Rat Rattus norvegicus P97756 505 55889 S443 N S V K L I P S W T T V I L V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519677 851 91898 S639 N S I K L I P S L T T V V R R
Chicken Gallus gallus XP_001234325 537 59761 S475 N S V K T I P S L P A V I L V
Frog Xenopus laevis NP_001082316 523 58635 S462 N S V K L I P S L T T V I L V
Zebra Danio Brachydanio rerio NP_001014361 434 48727 V375 F V P S L S A V I L V K A M L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_001021153 541 60786 R445 N C V R V I P R L D T L I L V
Sea Urchin Strong. purpuratus XP_785473 661 73509 E600 E E N C V L V E V S Q D E V D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.5 89.5 N.A. 93.4 93.6 N.A. 38.4 69.4 69.4 63.5 N.A. N.A. N.A. 42.8 35.7
Protein Similarity: 100 N.A. 99.5 91.2 N.A. 95.8 95.8 N.A. 46.5 79.3 80.1 76 N.A. N.A. N.A. 59.7 50.3
P-Site Identity: 100 N.A. 100 6.6 N.A. 100 93.3 N.A. 60 66.6 86.6 6.6 N.A. N.A. N.A. 60 0
P-Site Similarity: 100 N.A. 100 20 N.A. 100 100 N.A. 80 73.3 93.3 20 N.A. N.A. N.A. 73.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 10 0 0 0 10 0 10 0 0 % A
% Cys: 0 10 0 10 0 0 0 0 10 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 10 0 10 0 0 10 % D
% Glu: 10 10 0 0 10 10 10 10 0 0 0 0 19 0 0 % E
% Phe: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % H
% Ile: 0 0 10 0 0 73 0 0 10 0 0 0 64 0 0 % I
% Lys: 0 0 0 37 0 0 0 0 0 0 0 10 0 0 0 % K
% Leu: 0 10 0 0 64 10 0 0 37 10 0 10 0 64 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % M
% Asn: 73 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 10 0 19 0 0 0 73 0 0 10 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % Q
% Arg: 0 0 0 37 0 0 0 10 0 0 0 0 0 10 10 % R
% Ser: 0 64 0 19 0 10 0 64 0 19 0 0 0 0 0 % S
% Thr: 0 0 0 0 10 0 0 0 0 55 64 0 0 0 10 % T
% Val: 0 10 64 0 19 0 10 10 10 0 19 73 10 19 64 % V
% Trp: 0 0 0 0 0 0 0 0 37 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _